Home » InPlace™ Columns

InPlace™ Columns

Precise. Reproducible. Sustainable.

Chromatography columns for pilot-scale through clinical trials and commercial large-scale manufacturing. We offer several column hardware configurations depending on your biologic purification application.  Column design allows for easy column packing, unpacking, and cleaning in place processes. Precise reproducible and scalable packing performance can be achieved with axial compression methods or combined with flow packing depending on process requirements.

With our automated packing methods and axial compression technology, users can achieve precision-driven first-time right packing.  Expensive downtime and potential loss of product can result from packing errors.  You can always lean on us for guidance and support.  We have an extensive library of packing studies performed at-scale to provide guidance, which is continuously growing as we partner with resin manufacturers.  In addition, we offer on-site packing support to ensure you receive an exceptional user experience with our products.

If you have specific requirements, we can customize our columns for a more tailored solution. Contact us for more information.


  • Scalable column design from 20 cm – 200 cm (2 m); adjustable bed height up to 50 cm depending on column tube configuration.
  • Automated method-driven packing / unpacking in <2 hours
  • Compatible with all resin types, including hydroxyapatite resins
  • Precise reproducible packing performance
  • Ergonomic operation and compact footprint
  • Hoist-free operation with our column lifter (inquire for more information)
  • Low mechanical shear and minimal resin loss during resin transfer
  • Available with borosilicate glass, 316 L stainless steel, or acrylic column tubes
  • Basic and advanced packing motor console options depending on process requirements
  • Comprehensive documentation package for regulatory submissions

Column customization available (inquire for more information)

Ready to take your innovation to market?

Reach out to learn more about how we can help you with your downstream processing needs.